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KMID : 0385020040200020171
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Korean Journal of Laboratory Animal Science
2004 Volume.20 No. 2 p.171 ~ p.176
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Effects of Ultrasound Application to Sciatic Nerve Injured Rats on Enhancement of the Sciatic Function Index
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Kim Young-Chul
Kim Dong-Dae
Kim Jin-Sang
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Abstract
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To evaluate the effects of low-intensity ultrasound application to sciatic nerve-injured rats on foot function recovery, various continuous-wave ultrasound treatments with intensities of 0.2 W/cm2, 0.5 W/ cm2 and 1.0 W/cm2 operated at 1 MHz, and sham (control) treatment were applied to the opposite inside of the nerve injury site for 1 min every other day with a transducer moving speed of 2 cm/sec. Sciatic function index (SFI) was measured by walking track analysis. Progressive foot function recovery was identified in a time-dependent manner after sciatic nerve injury, the degrees of food function recovery were faster in all the experimental groups in comparison with the control group. SFI scores for 0.5 W/cm2 and 1 W/cm2 intensity ultrasound application groups were significantly higher than that for the control group after 14 days post-injury (p<0.05). SFI score for 0.2 W/cm2 intensity ultrasound application group was also significantly higher than that for the control group after 28 days post-injury (p<0.05). These results suggest that low-intensity ultrasound application after peripheral nerve injury may be an effective therapeutic method in a clinical practice.
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KEYWORD
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Ultrasound, Sciatic nerve injury, Sciatic function index, Foot function recovery
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